Exposing the human nude phenotype
J Frank, C Pignata, AA Panteleyev, DM Prowse… - Nature, 1999 - nature.com
J Frank, C Pignata, AA Panteleyev, DM Prowse, H Baden, L Weiner, L Gaetaniello…
Nature, 1999•nature.comThe recent discovery of the human counterpart of the hairless mouse phenotype has helped
our understanding of the molecular genetics of hair growth. But there are no reports of a
defect in the human homologue of the best known of the 'bald'mouse phenotypes, the nude
mouse. This may be because affected individuals are so gravely ill from the accompanying
immunodeficiency that their baldness goes unnoticed. We have carried out a genetic
analysis that reveals a human homologue of the nude mouse.
our understanding of the molecular genetics of hair growth. But there are no reports of a
defect in the human homologue of the best known of the 'bald'mouse phenotypes, the nude
mouse. This may be because affected individuals are so gravely ill from the accompanying
immunodeficiency that their baldness goes unnoticed. We have carried out a genetic
analysis that reveals a human homologue of the nude mouse.
Abstract
The recent discovery of the human counterpart of the hairless mouse phenotype has helped our understanding of the molecular genetics of hair growth. But there are no reports of a defect in the human homologue of the best known of the ‘bald’ mouse phenotypes, the nude mouse. This may be because affected individuals are so gravely ill from the accompanying immunodeficiency that their baldness goes unnoticed. We have carried out a genetic analysis that reveals a human homologue of the nude mouse.
nature.com
