Clinical, biochemical, and genetic characterization of type III hereditary angioedema in 13 Northwest Spanish families
BACKGROUND: A new variant of hereditary angioedema has been reported during the last
decade. Three main characteristics distinguish it from classic hereditary angioedema:
normal C1 inhibitor activity, predominance in women, and different genetic alterations.
OBJECTIVE: To assess the symptoms, laboratory findings, and treatment of a population
with type III hereditary angioedema from Northwest Spain. METHODS: We studied 29
patients (26 female and 3 male) from 13 different families. RESULTS: The 26 female patients …
decade. Three main characteristics distinguish it from classic hereditary angioedema:
normal C1 inhibitor activity, predominance in women, and different genetic alterations.
OBJECTIVE: To assess the symptoms, laboratory findings, and treatment of a population
with type III hereditary angioedema from Northwest Spain. METHODS: We studied 29
patients (26 female and 3 male) from 13 different families. RESULTS: The 26 female patients …