[HTML][HTML] Mammary development and breast cancer: a Wnt perspective
QC Yu, EM Verheyen, YA Zeng - Cancers, 2016 - mdpi.com
QC Yu, EM Verheyen, YA Zeng
Cancers, 2016•mdpi.comThe Wnt pathway has emerged as a key signaling cascade participating in mammary
organogenesis and breast oncogenesis. In this review, we will summarize the current
knowledge of how the pathway regulates stem cells and normal development of the
mammary gland, and discuss how its various components contribute to breast carcinoma
pathology.
organogenesis and breast oncogenesis. In this review, we will summarize the current
knowledge of how the pathway regulates stem cells and normal development of the
mammary gland, and discuss how its various components contribute to breast carcinoma
pathology.
The Wnt pathway has emerged as a key signaling cascade participating in mammary organogenesis and breast oncogenesis. In this review, we will summarize the current knowledge of how the pathway regulates stem cells and normal development of the mammary gland, and discuss how its various components contribute to breast carcinoma pathology.
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