Activation of extracellular signal regulated protein kinase by neuropeptide Y and pancreatic polypeptide in CHO cells expressing the NPY Y1, Y2, Y4 and Y5 receptor …
DE Mullins, X Zhang, BE Hawes - Regulatory peptides, 2002 - Elsevier
Neuropeptide Y (NPY), 36-amino acid amidated peptide expressed in central and peripheral
neurons, regulates a variety of physiological activities, including food intake, energy
expenditure, vasoconstriction, anxiolysis, nociception and ethanol consumption. NPY binds
to a family of G-protein coupled receptors whose activation results in inhibition of adenylyl
cyclase activity. To more fully characterize the signal transduction pathways utilized by the
NPY receptor subtypes, the pathways leading to phosphorylation of the extracellular signal …
neurons, regulates a variety of physiological activities, including food intake, energy
expenditure, vasoconstriction, anxiolysis, nociception and ethanol consumption. NPY binds
to a family of G-protein coupled receptors whose activation results in inhibition of adenylyl
cyclase activity. To more fully characterize the signal transduction pathways utilized by the
NPY receptor subtypes, the pathways leading to phosphorylation of the extracellular signal …