Association between serum MicroRNAs and magnetic resonance imaging measures of multiple sclerosis severity

K Regev, BC Healy, F Khalid, A Paul, R Chu… - JAMA …, 2017 - jamanetwork.com
Importance MicroRNAs (miRNAs) are promising multiple sclerosis (MS) biomarkers.
Establishing the association between miRNAs and magnetic resonance imaging (MRI)
measures of disease severity will help define their significance and potential impact.
Objective To correlate circulating miRNAs in the serum of patients with MS to brain and
spinal MRI. Design, Setting, and Participants A cross-sectional study comparing serum
miRNA samples with MRI metrics was conducted at a tertiary MS referral center. Two …